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福参(Angelica morri Hayata)色原酮化合物的结构确定
引用本文:孙视,孔令义,张涵庆,贺善安.福参(Angelica morri Hayata)色原酮化合物的结构确定[J].中国天然药物,2005,3(2):97-100.
作者姓名:孙视  孔令义  张涵庆  贺善安
作者单位:1. 江苏省中国科学院植物研究所,南京中山植物园,南京 210014;中国药科大学天然药物化学教研室,南京 210038
2. 中国药科大学天然药物化学教研室,南京 210038
3. 江苏省中国科学院植物研究所,南京中山植物园,南京 210014
摘    要:目的:研究福参的活性成分。方法:采用柱色谱及重结晶法进行分离纯化,通过光谱法进行结构鉴定,化学沟通法确定绝对构型,结果:分得一个色原酮divaricatol(1)结论:化合物1首次从当归属植物中分得、到目前为止.福参中分离到的色原酮类化合物与中药防风的基源植物防风(Saposhnikovia diavaricata Schischk.Syn.Ledebouriella seseloides Wolff)中的色原酮活性成分很相近。

关 键 词:福参  divaricatol  色原酮化合物  中药材  化学结构  活性成分

Structural Determination of Chromone from Angelica morri Hayata
SUN Shi,KONG Ling-yi,ZHANG Han-qing,HE Shan-an.Structural Determination of Chromone from Angelica morri Hayata[J].Chinese JOurnal of Natural Medicines,2005,3(2):97-100.
Authors:SUN Shi  KONG Ling-yi  ZHANG Han-qing  HE Shan-an
Abstract:AIM: To study the bioactive constituents of Angelica morri Hayata. METHODS: The constituent was isolated and purified by column chromatography and recrystallization; the structure was identified by spectral analysis, absolute configuration was determined based on chemical correlation. RESULT: One chromone was obtained and identified as divaricatol(1). CONCLUSION: Compound 1 was isolated from Angelica L. for the first time. So far, chromones from Angelica morri Hayata are similar to bioactive constituents from original plants of Radix Saposhinkoviae, Saposhnikovia diavaricata Schischkin (Ledebouriella seseloides Wolff).
Keywords:Angelica morri Hayata  Divaricatol  Umbelliferae
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