| HPLC法测定熊胆救心滴丸中人参皂苷Rg_1和人参皂苷Re的含量 |
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| 引用本文： | 赫玉芳,南敏伦,司学玲,赵全成.HPLC法测定熊胆救心滴丸中人参皂苷Rg_1和人参皂苷Re的含量[J].沈阳药科大学学报,2005,22(1):26-28,32. |
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| 作者姓名： | 赫玉芳 南敏伦 司学玲 赵全成 |
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| 作者单位： | 1. 吉林天药科技股份有限公司,吉林,长春,130012
2. 吉林省西洋参集团有限公司,吉林,靖宇,135200 |
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| 摘 要： | 目的建立熊胆救心滴丸中人参皂苷Rg1和人参皂苷Re的含量测定方法。方法采用DikmaODSC18柱 ,流动相为乙腈 0 0 5 % (φ)磷酸溶液 (V∶V =2 1∶79) ,检测波长为 2 0 3nm。 结果人参皂苷Rg1在 0 3～ 2 4 μg内其含量与峰面积呈良好的线性关系 ,平均回收率为 98 8% ,RSD为1 78%。人参皂苷Re在 0 2～ 1 6 μg内其含量与峰面积呈良好的线性关系 ,平均回收率为10 1 5 % ,RSD为 2 2 9%。结论测定方法准确、重现性好 ,可作为熊胆救心滴丸制剂的质量控制方法
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| 关 键 词： | 高效液相色谱法 人参皂苷Rg1 人参皂苷Re 熊胆救心滴丸 |
| 文章编号： | 1006-2858(2005)01-0026-03 |
Determination of ginsenoside Rg1 and gsinenoside Re in the Xiongdanjiuxin Dropping Pills by HPLC |
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| HE Yu-fang ,NAN Min-lun ,SI Xue-ling ,ZHAO Quan-cheng.Determination of ginsenoside Rg1 and gsinenoside Re in the Xiongdanjiuxin Dropping Pills by HPLC[J].Journal of Shenyang Pharmaceutical University,2005,22(1):26-28,32. |
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| Authors: | HE Yu-fang NAN Min-lun SI Xue-ling ZHAO Quan-cheng |
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| Institution: | HE Yu-fang 1,NAN Min-lun 1,SI Xue-ling 2,ZHAO Quan-cheng 1 |
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| Abstract: | Objective To establish the HPLC method for the determination of ginsenoside Rg 1 and ginsenoside Re in the Xiongdanjiuxin Dropping Pills.Method The chromatographic conditions included the column of Dikma ODS C 18 column (4.6 mm×250 mm),the mobile phase was acetonitrile-0.05%(φ)phosphoric acid solntion (V∶V=21∶79),the detection wavelength was set at 203 nm and the column temperature was 25 ℃.Results The linear range of ginsenoside Rg 1 was 0.3～2.4 μg and Re was 0.2～1.6 μg respectively.The average recovery of ginsenoside Rg 1 and ginsenoside Re were 99.8% with RSD 1.78% and 101.5% with RSD 2.29%.Conclusion The mothod is accurate and can be used as a determination of ginsenoside Rg 1 and ginsenoside Re in the Xiongdanjiuxin Dropping Pills. |
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| Keywords: | HPLC ginsenoside Rg 1 gsinenoside Re Xiongdanjiuxin Dropping Pills |
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