2016—2018年中国医科大学附属第一医院门诊药房麻醉药品的使用情况分析

目的 分析2016—2018年中国医科大学附属第一医院门诊药房麻醉药品的使用情况和变化趋势，为临床合理使用麻醉药品提供参考。方法 对2016—2018年中国医科大学附属第一医院门诊药房麻醉药品的使用数量、销售金额、用药频度（DDDs）、日均费用（DDC）以及排序比（B/A）进行统计学分析。结果 2016—2018年门诊药房麻醉药品消耗量持续增长，麻醉药品的销售金额排名稳定，盐酸羟考酮缓释片（10、40 mg）的销售金额排名分别位列前两位。各药品的DDDs排名变化不明显，芬太尼透皮贴剂（4.2 mg）的DDDs连续3年排名第1位。DDC持续下降，DDC值最高的为盐酸羟考酮缓释片（40 mg），最低的为盐酸布桂嗪片。B/A最低的为盐酸羟考酮缓释片（10 mg），最高的为芬太尼透皮贴剂（4.2 mg），其他麻醉药品的B/A值都在1左右。结论 中国医科大学附属第一医院门诊药房麻醉药品的使用基本合理。

Analysis on usage of narcotic drugs in outpatient of the First Hospital of China Medical University from 2016 to 2018

Objective To investigate the usage and variation tendency of narcotic drugs in outpatient of the First Hospital of China Medical University from 2016 to 2018, in order to provide reference for rational use of drugs in clinic. Methods The usage of narcotic drugs in outpatient of the First Hospital of China Medical University from 2016 to 2018 were collected, and consumption quantity, consumption sum, defined daily dose system (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were calculated and compared. Results The total consumption quantity of narcotic drugs showed a steady increase from 2016 to 2018. Consumption sum of narcotic drugs ranked stable, and consumption sum of Oxycodone Hydrochloride Prolonged-release Tablets (10 and 40 mg) were ranked the top two. The DDDs ranking of narcotic drugs did not change significantly. DDDs of Fentanyl Transdermal Patches (4.2 mg) was ranked the first for three consecutive years. DDC of narcotic drugs was decreased in the past 3 years. DDC of Oxycodone Hydrochloride Prolonged-release Tablets (40 mg) was the highest, while DDC of Bucinnazine Hydrochloride Tablets was the lowest. B/A of Oxycodone Hydrochloride Prolonged-release Tablets (10 mg) was the lowest, while B/A of Fentanyl Transdermal Patches (4.2 mg) was the highest, and B/A of other narcotic drugs were close to 1. Conclusion The utilization of narcotic drugs in outpatient of the First Hospital of China Medical University was basically rational.K