| 三七素的药理作用研究进展 |
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| 引用本文： | 张希,王文倩,许旭东,田瑜,尚海. 三七素的药理作用研究进展[J]. 现代药物与临床, 2019, 34(10): 3192-3196 |
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| 作者姓名： | 张希 王文倩 许旭东 田瑜 尚海 |
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| 作者单位： | 哈尔滨商业大学 药学院(药物工程技术研究中心),黑龙江 哈尔滨 150076;中国医学科学院 北京协和医学院药用植物研究所,北京 100193;天津药物研究院,天津,300193;中国医学科学院 北京协和医学院药用植物研究所,北京,100193 |
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| 基金项目： | 北京市自然科学基金资助项目（7192129）；中国医学科学院医学与健康科技创新工程项目（2016-I2M-1-012） |
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| 摘 要： | 三七素是一种天然存在的非蛋白氨基酸,主要存在于三七中。三七素具有多种药理作用,文献报道最多的是止血作用。此外,三七素还具有神经保护作用、减轻糖尿病肾病损伤作用、抗炎作用及降血糖等作用。近年来对三七素的相关研究逐渐增多,主要综述三七素的药理作用研究进展,期望为今后三七素的进一步研究和开发利用提供参考。
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| 关 键 词： | 三七素 药理作用 研究进展 |
| 收稿时间： | 2019-09-18 |
Research progress on pharmacological effects of dencichine |
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| ZHANG Xi,WANG Wen-qian,XU Dong-xu,TIAN Yu and SHANG Hai. Research progress on pharmacological effects of dencichine[J]. Drugs & Clinic, 2019, 34(10): 3192-3196 |
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| Authors: | ZHANG Xi WANG Wen-qian XU Dong-xu TIAN Yu SHANG Hai |
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| Affiliation: | College of Pharmacy(Pharmaceutical Engineering Technology Research Center), Harbin University of Commerce, Harbin 150076, China;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China,Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China,Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China,Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China and Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China |
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| Abstract: | Dencichine is a naturally occurring non-protein amino acid mainly found in Panax pseudo-ginseng Wall. var. notoginseng (Burkill) Hoo & Tseng. Dencichine has a variety of biological activities, and the most reported in the literature is hemostatic activity. In addition, dencichine also has neuroprotective activities, alleviation of the damage of diabetic nephropathy, anti-inflammatory effects, and hypoglycemic effects. In recent years, the related research on dencichine has gradually increased. Research progress on pharmacological effects of dencichine is reviewed in this paper, and to provide reference for further research, development, and utilization of the future. |
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| Keywords: | dencichine pharmacological effects research progress |
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