| 杜仲的活性成分及其药动学研究进展 |
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| 引用本文： | 穆文碧,陈启洪,段灿灿,张建永. 杜仲的活性成分及其药动学研究进展[J]. 中国现代应用药学, 2019, 36(20): 2598-2604 |
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| 作者姓名： | 穆文碧 陈启洪 段灿灿 张建永 |
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| 作者单位： | 遵义医科大学药学院, 贵州 遵义 563009,遵义医科大学药学院, 贵州 遵义 563009,遵义医科大学基础药理教育部重点实验室暨特色民族药教育部国际合作联合实验室, 贵州 遵义 563003,遵义医科大学药学院, 贵州 遵义 563009 |
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| 基金项目： | 国家自然科学基金项目（81560736）；贵州省国内一流学科建设（药学）（YLXKJS-YS-05）；贵州省教育厅科技拔尖人才支持项目（黔教合KY字[2017]078） |
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| 摘 要： | 杜仲中主要含有木脂素类、环烯醚萜类、苯丙素类、黄酮类等化学成分，现代研究发现杜仲呈现多种显著的生物活性，因此具有较强的药用价值。本文总结了近年来国内外发现的杜仲中化学成分，进一步梳理活性成分，对杜仲及其活性成分的药动学行为进行归纳分析，为今后杜仲的深入研究提供参考。
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| 关 键 词： | 杜仲 化学成分 活性成分 药动学 |
| 收稿时间： | 2019-02-28 |
| 修稿时间： | 2019-06-29 |
Advances in Research on Active Ingredients and Pharmacokinetics of Eucommia Ulmoides Oliv |
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| MU Wenbi,CHEN Qihong,DUAN Cancan and ZHANG Jianyong. Advances in Research on Active Ingredients and Pharmacokinetics of Eucommia Ulmoides Oliv[J]. The Chinese Journal of Modern Applied Pharmacy, 2019, 36(20): 2598-2604 |
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| Authors: | MU Wenbi CHEN Qihong DUAN Cancan ZHANG Jianyong |
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| Affiliation: | School of Pharmacy, Zunyi Medical University, Zunyi 563009, China,School of Pharmacy, Zunyi Medical University, Zunyi 563009, China,Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563003, China and School of Pharmacy, Zunyi Medical University, Zunyi 563009, China |
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| Abstract: | The chemical components found in Eucommia ulmoides Oliv mainly includes lignans, iridoids, phenylpropanoids, flavonoids and et al. Modern research showed Eucommia ulmoides Oliv exhibits various biological activities and strong medicinal value. This paper reviewed the chemical constituents of Eucommia ulmoides Oliv in recent years, and the active ingredients were screened. Further the pharmacokinetics of these components from Eucommia ulmoides Oliv were summarized and analyzed, which will provide a new reference for the further study of Eucommia ulmoides Oliv. |
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| Keywords: | Eucommia ulmoides Oliv chemical composition activity component pharmacokinetic |
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