黄藤素软胶囊联合聚甲酚磺醛溶液治疗慢性宫颈炎的疗效观察

目的考察黄藤素软胶囊联合聚甲酚磺醛溶液治疗慢性宫颈炎的治疗效果。方法选取2016年6月—2018年6月在成都市新都区妇幼保健院诊的慢性宫颈炎患者196例,随机分为对照组和治疗组,每组各98例。对照组患者用聚甲酚磺醛溶液清洁宫颈及宫颈管,并将含药液纱布敷于病变组织,10min后取出,2次/周。治疗组在对照组基础上餐后半小时口服黄藤素软胶囊,3粒/次,3次/d。两组患者均连续治疗4周。观察两组患者临床疗效,同时比较治疗前后两组患者宫颈上皮愈合情况、临床症状评分、体征改善所需时间和复发率。结果治疗后,对照组和治疗组临床有效率分别为84.69%和92.86%,两组比较差异具有统计学意义(P0.05)。治疗后,两组患者脓性分泌物、接触性出血和腰骶酸痛评分均显著降低(P0.05),且治疗组这些评分明显低于对照组(P0.05)。治疗后,治疗组宫颈修复时间、分泌物改善时间、出血消失时间、腰骶酸痛消失时间均显著早于对照组(P0.05)。治疗后,治疗组患者复发率为1.02%,显著低于对照组患者的8.16%,两组比较差异具有统计学意义(P0.05)。结论藤素软胶囊联合聚甲酚磺醛溶液治疗慢性宫颈炎疗效显著,复发率低,且副作用低。

Clinical observation of Huangtengsu Soft Capsules combined with policresulen solutionon in treatment of chronic cervicitis

Objective To investigate the therapeutic effect of Huangtengsu Soft Capsules combined with policresulen solutionon in treatment of chronic cervicitis. Methods Patients (196 cases) with chronic cervicitis in Chengdu Xindu Maternal & Child Health Care Hospital from June 2016 to June 2018 were randomly divided into control and treatment groups, and each group had 98 cases. Patients in the control group were administered with Policresulen Solution to clean cervix and cervical canal, and drug-containing gauze was applied to lesion tissues for 10 min, twice weekly. Patients in the treatment group were po administered with Huangtengsu Soft Capsules on the basis of the control group half an hour after meal, 3 grains/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical efficacy was evaluated, and clinical symptoms scores, the disappearance time of symptoms and recurrence rates in two groups before and after treatment were compared. Results After treatment, the clinical efficacy and in the control and treatment groups was 84.69% and 92.86% respectively, and there were differences between two groups (P<0.05). After treatment, the purulent secretion, contact hemorrhage, and lumbosacral soreness scores in two groups were significantly decreased (P<0.05), and these scores in the treatment group were significantly lower than those in the control group (P<0.05). After treatment, the time of cervical repair, secretion improvement, bleeding disappeared and lumbosacral pain disappeared in the treatment group was significantly earlier than that in the control group (P<0.05). After treatment, the recurrence rate in the treatment group was 1.02%, which was significantly lower than 8.16% in the control group, with significant difference between two groups (P<0.05). Conclusion Huangtengsu Soft Capsules combined with policresulen solutionon in treatment of chronic cervicitis has a significant effect with low recurrence rate and side effects.