2012-2017年西充县人民医院药品不良反应报告分析

目的 分析西充县人民医院2012-2017年药品不良反应（ADR）发生的规律和特点，为进一步加强该院ADR监测水平和临床安全用药提供参考。方法 对西充县人民医院2012-2017年ADR报告进行整理汇总，对患者性别组成、年龄分布、给药途径，ADR类型以及药品种类等进行统计分析。结果 2012-2017年ADR报告例数逐年上升，共纳入843例ADR报告进行分析，其中男性占50.42%，女性占49.58%；老年患者ADR发生率占比最高；抗感染药物类、消化系统类药物、心血管系统类药物以及电解质和营养药ADR发生率较高，但抗感染药物ADR发生风险呈现逐年下降的趋势。结论 近6年来西充县人民医院ADR报告质量逐年提升，但仍需持续提高药品管理水平，规范医疗用药的合理性和安全性，减少患者用药的不适感和安全风险，以期促进该院不良反应监测工作上升到一个新台阶。

Analysis of adverse drug reactions in Xichong County People's Hospital annual report an 2012-2017

Objective To analyze the regularity and characteristics of the adverse drug reaction (ADR) in Xichong County People''s Hospital from 2012 to 2017, and provide reference for further strengthening the ADR monitoring level and clinical safety medication in our hospital. Methods The ADR reports of this hospital from 2012 to 2017 was compiled and summarized, and the patient''s gender composition, age distribution, administration route, ADR type and drug type were statistically analyzed. Results The number of ADR reports in 2012-2017 increased year by year. A total of 843 ADR reports were included for analysis. Among them, 50.42% were men and 49.58% were women. The incidence of ADR was the highest in elderly patients. The ADR incidence of anti-infective drugs, digestive system drugs, cardiovascular system drugs and electrolytes and nutrients ADR was higher, but the risk of antiinfective drugs ADR was in a decreasing trend year by year. Conclusion In the past six years, the quality of ADR reports in Xichong County People''s Hospital has increased by yeard, but it is still necessary to continuously improve the level of drug management, standardize the rationality and safety of medical drugs, reduce the discomfort and safety risks of patients, in order to promote the monitoring of adverse reactions in this hospital to a new step.