| 真菌性眼内炎的药物和手术治疗进展 |
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| 引用本文： | 陈星,杨勋. 真菌性眼内炎的药物和手术治疗进展[J]. 国际眼科杂志, 2019, 19(12): 2064-2067 |
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| 作者姓名： | 陈星 杨勋 |
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| 作者单位： | 中国江苏省无锡市第九人民医院眼科; 中国江苏省苏州市,苏州大学附属理想眼科医院眼底眼外伤科,中国江苏省苏州市,苏州大学附属理想眼科医院眼底眼外伤科 |
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| 摘 要： | 真菌性眼内炎的治疗预后通常较差，其药物和手术治疗目前比较混乱，一直在探索中。传统药物有两性霉素B、氟康唑、氟胞嘧啶。新一代药物包括两性霉素B脂质体、伏立康唑、卡泊芬净。玻璃体切割术联合全身或局部应用药物对治疗真菌性眼内炎尤为重要。本文就目前真菌性眼内炎的药物和手术治疗进行综述。
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| 关 键 词： | 真菌性 眼内炎 治疗 药物 玻璃体切割术 |
| 收稿时间： | 2019-04-14 |
| 修稿时间： | 2019-11-04 |
Advances in drugs and surgical treatment of fungal endophthalmitis |
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| Xing Chen and Xun Yang. Advances in drugs and surgical treatment of fungal endophthalmitis[J]. International Eye Science, 2019, 19(12): 2064-2067 |
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| Authors: | Xing Chen and Xun Yang |
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| Affiliation: | Department of Ophthalmology, Wuxi 9th People''s Hospital, Wuxi 214062, Jiangsu Province, China; Department of Fundus Diseases and Ocular Trauma, LiXiang Eye Hospital of Soochow University, Suzhou215021, Jiangsu Province, China and Department of Fundus Diseases and Ocular Trauma, LiXiang Eye Hospital of Soochow University, Suzhou215021, Jiangsu Province, China |
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| Abstract: | The prognosis of fungal endophthalmitis is usually poor. Currently, it is confusing in the drugs and surgical treatment and has been explored and progressed. Traditional drugs include amphotericin B, fluconazole and flucytosine. A new generation of drugs includes liposomal amphotericin B, Voriconazole, and caspofungin. Vitrectomy combined with systemic, topical and intraocular application of drugs is particularly important for the treatment of fungal endophthalmitis. This article reviews the current and ongoing development of drugs and surgical treatment of fungal endophthalmitis. |
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| Keywords: | fungal endophthalmitis treatment drug vitrectomy |
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