| 黄芪建中汤及其组方单味药化学成分与体内代谢研究进展 |
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| 引用本文： | 靳志东,李科,李爱平,秦雪梅,刘月涛.黄芪建中汤及其组方单味药化学成分与体内代谢研究进展[J].中草药,2019,50(18):4495-4501. |
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| 作者姓名： | 靳志东 李科 李爱平 秦雪梅 刘月涛 |
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| 作者单位： | 山西大学 中医药现代研究中心, 山西 太原 030006,山西大学 中医药现代研究中心, 山西 太原 030006,山西大学 中医药现代研究中心, 山西 太原 030006,山西大学 中医药现代研究中心, 山西 太原 030006,山西大学 中医药现代研究中心, 山西 太原 030006 |
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| 基金项目： | 国家自然科学基金资助项目（31570346）；国家自然科学基金资助项目（81703697） |
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| 摘 要： | 黄芪建中汤出自东汉张仲景的《金匮要略》，全方由黄芪、白芍、桂枝、甘草、生姜、大枣、饴糖7味中药组成。临床上主要用于治疗消化性溃疡、十二指肠溃疡、胃食管反流等疾病。通过回顾近年来黄芪建中汤及其组方单味药的研究文献，对黄芪建中汤及其组方中单味药的主要化学成分及其体内代谢途径、代谢反应和代谢产物进行综述，为黄芪建中汤的物质基础研究提供科学参考。
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| 关 键 词： | 黄芪建中汤 化学成分 体内代谢 代谢途径 代谢产物 |
| 收稿时间： | 2019/2/27 0:00:00 |
Research progress on chemical composition and metabolism of Huangqi Jianzhong Decoction and its constituent herbal medicines |
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| JIN Zhi-dong,LI Ke,LI Ai-ping,QIN Xue-mei and LIU Yue-tao.Research progress on chemical composition and metabolism of Huangqi Jianzhong Decoction and its constituent herbal medicines[J].Chinese Traditional and Herbal Drugs,2019,50(18):4495-4501. |
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| Authors: | JIN Zhi-dong LI Ke LI Ai-ping QIN Xue-mei and LIU Yue-tao |
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| Institution: | Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China,Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China,Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China,Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China and Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China |
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| Abstract: | Huangqi Jianzhong Decoction is recorded in Synopsis of the Golden Chamber by Zhong-jing Zhang in the Eastern Han Dynasty. It consists of seven herbs including Astragali Radix, Cinnamomi Ramulus, Paeoniae Radix Alba, Jujubae Fructus, Zingiberis Rhizoma Recens, Glycyrrhizae Radix et Rhizoma and Saccharum granorum. Clinically, it is mainly used to treat peptic ulcer, duodenal ulcer, gastroesophageal reflux and other diseases. By reviewing the research literatures of Huangqi Jianzhong Decoction and its components in recent years, the main chemical constituents, metabolic pathways, metabolic reactions and metabolites of Huangqi Jianzhong Decoction and its components were summarized provide scientific reference for the material basis research of Huangqi Jianzhong Decoction. |
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| Keywords: | Huangqi Jianzhong Decoction chemical composition metabolism in vivo metabolic pathways metabolites |
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