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臭牡丹的镇痛作用的研究
引用本文:刘建新,周青,连其深,何尉,叶和杨,黄贤华.臭牡丹的镇痛作用的研究[J].赣南医学院学报,2003,23(2):119-121.
作者姓名:刘建新  周青  连其深  何尉  叶和杨  黄贤华
作者单位:赣南医学院药理学教研室,江西,赣州,341000
摘    要:目的:研究臭牡丹的镇痛作用。方法:采用热板法、醋酸扭体法、电刺激致痛法观察药物的镇痛作用。结果:臭牡丹提取液明显抑制冰醋酸引起的小鼠扭体反应;显著提高热板法和电刺激致痛小鼠的痛阈;纳洛酮可拮抗吗啡的镇痛作用,但不能拮抗臭牡丹根提取液的镇痛作用。结论:臭牡丹有镇痛作用,此作用与其激动中枢阿片受体无关。

关 键 词:臭牡丹  镇痛
文章编号:1001-5779(2003)02-0119-03
修稿时间:2002年4月6日

A Study of the Anagesic Effect of Clerodendron Bungei Steud
LIU Jian xing,ZHOU Qing,LIAN Qi shen,et al.A Study of the Anagesic Effect of Clerodendron Bungei Steud[J].Journal of Gannan Medical College,2003,23(2):119-121.
Authors:LIU Jian xing  ZHOU Qing  LIAN Qi shen  
Abstract:objective:The elementary study on analgesic effect of clerodendron bungei steud.Method:the analgesic were observed through the methods that caused analgesic effect in mice by hot board or by acetic acid inducing mice writhing,and the analgesic effects of clerodendron bungei steud with nalotone were observed by hot board.Result:the solution of clerodendron bungei steud inhibited the activities on mice writhing induced by acetic acid and distinctly increased mice pain threshold by hot board,and clerodendron bungei steud with nalotone distinctly inhibited mice pain caused by hot board.Conclusion:clerodendron bungei steud possess the analgesic effects independently of opiate receptor.
Keywords:clerodendron bungei steud  analgesia
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