| ACCURACY OF SERUM – ASCITES ALBUMIN GRADIENT IN THE AETIOLOGICAL DIAGNOSIS OF ASCITES |
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ACCURACY OF SERUM – ASCITES ALBUMIN GRADIENT IN THE AETIOLOGICAL DIAGNOSIS OF ASCITES |
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| Authors: | AK SETH R RANGARAO R PAKHETRA V BASKARAN PVS RANA S RAJAMANI |
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| Institution: | 1. Division of Medicine, Akershus University Hospital, Lørenskog, Norway;2. Center for Heart Failure Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway;3. Multidiciplinary Laboratory Medicine and Medical Biochemistry, Akershus University Hospital, Lørenskog, Norway;4. Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway |
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| Abstract: | 50 adults with ascites admitted to our hospital were studied. Simultaneous samples of ascitic fluid and blood were collected and subjected to analysis including ascitic fluid total protein and serum ascites albumin gradient The cut off value of serum-ascites albumin gradient for differentiating between high and low gradient was taken as 1.1 gm % and of ascitic fluid protein for differentiating exudate and transudate as 2.5 gm%. The sensitivity, specificity, positive predictive value and negative predictive value of high gradient and transudative ascites in diagnosing portal hypertension were 943%, 60%, 84.6%, 81.8% and 62.9%, 133%, 91.7% and 50% respectively. High gradient ascites is a sensitive test in the diagnosis of portal hypertension as a cause of ascites. The exudate-transudate approach has severe limitations in the differential diagnosis of ascites.KEY WORDS: Albumin Gradient, Ascites, High Gradient Ascites, Serum-Ascites |
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| Keywords: | Albumin Gradient Ascites High Gradient Ascites Serum-Ascites |
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