纳米碳示踪剂在乳腔镜腋窝淋巴结清扫中的应用

目的:探讨纳米碳示踪剂技术在乳腔镜腋窝淋巴结清扫中的应用价值。方法:收集2015年6月至2018年6月我院住院的cN0-1期乳腺癌患者共60例，将患者随机分为纳米碳辅助乳腔镜组（观察组）和常规乳腔镜组（对照组），每组30例，分析纳米碳示踪的前哨淋巴结在患者中的检出结果，并比较两组清扫淋巴结情况、手术时间及术后并发症的发生率。结果:纳米碳示踪剂辅助乳腔镜腋窝淋巴结清扫术的检出率为100%，灵敏度为92.31%、假阴性率为7.69%、准确率为96.67%。对于清扫出的淋巴结总数及微小淋巴结数，观察组明显高对照组（P<0.05）；而在手术时间以及术后并发症的发生率方面，两组间比较差异无统计学意义（P>0.05）。结论:相较于常规乳腔镜腋窝淋巴结清扫术，纳米碳示踪剂能提高淋巴结检出率及转移淋巴结的阳性检出率，尤其是对微小淋巴结的检出率，并且不会增加额外手术时间和术后并发症。

Application of nano-carbon tracer in the breast mastoscopic axillary lymph node dissection

Objective:To investigate the application value of nano-carbon tracer technology in breast mastoscopic axillary lymph node dissection.Methods:A total of 60 patients with cN0-1 breast cancer who were hospitalized in our hospital from June 2015 to June 2018 were enrolled.The patients were divided into the nano-carbon-assisted mastoscopic group(the observation group)and conventional mastoscopic group(control group)randomly.Each group had 30 cases,and we analyzed the detection results of sentinel lymph nodes in patients with nano-carbon tracers,and compared the two groups of lymph node dissection,operation time and incidence of postoperative complications.Results:The detection rate of nano-carbon tracer assisted mammoscopic axillary lymph node dissection was 100%.The sensitivity was 92.31%.The false negative rate was 7.69%,and the accuracy was 96.67%.In terms of the total number of lymph nodes and micro-lymph nodes,the observation group was significantly higher than the control group(P<0.05),but there was no significant difference between the two groups in the operation time and the incidence of postoperative complications(P>0.05).Conclusion:Compared with conventional mastoscopic axillary lymph node dissection,nano-carbon tracers can increase the detection rate of lymph nodes and the positive detection rate of metastatic lymph nodes,especially the detection rate of micro-lymph nodes,and would not increase the extra operation time and incidence of postoperative complications.