| 五虎汤6种活性成分对离体豚鼠气管平滑肌的作用 |
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| 引用本文： | 迟天燕,纪雪飞,夏明钰,荣语媚,邱峰,邹莉波.五虎汤6种活性成分对离体豚鼠气管平滑肌的作用[J].中国实验方剂学杂志,2009,15(3):52-55. |
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| 作者姓名： | 迟天燕 纪雪飞 夏明钰 荣语媚 邱峰 邹莉波 |
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| 作者单位： | 沈阳药科大学,辽宁,沈阳,110016 |
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| 摘 要： | 目的:观察灌胃五虎汤制剂后大鼠体内出现的6种化学成分麻黄碱、甘草酸、甘草次酸、龙脑、松油醇、苯乙醇的平喘作用。方法:采用豚鼠离体气管螺旋条法筛选6种化学成分的平喘作用。结果:6种物质对组胺所致豚鼠气管平滑肌的收缩均有抑制作用。结论:以上成分为五虎汤平喘作用的物质基础。
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| 关 键 词： | 五虎汤 平喘 豚鼠 |
| 收稿时间： | 4/8/2008 12:00:00 AM |
Effect of Six Extractions from Wuhu Decoction on Isolated Tracheal Smooth Muscle in Guinea Pig |
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| CHI Tian-yan,JI Xue-fei,XIA Ming-yu,RONG Yu-mei,QUI Feng,ZOU Li-bo.Effect of Six Extractions from Wuhu Decoction on Isolated Tracheal Smooth Muscle in Guinea Pig[J].China Journal of Experimental Traditional Medical Formulae,2009,15(3):52-55. |
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| Authors: | CHI Tian-yan JI Xue-fei XIA Ming-yu RONG Yu-mei QUI Feng ZOU Li-bo |
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| Institution: | Shenyang Pharmaceutical University,Shenyang 110016,China |
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| Abstract: | Objective:To study the effect of ephedrine,glycyrrhizic acid,glycyrrhetinic acid,borneol,terpineol and phenethyl alcohol which were extracted from Wuhu Decoction on isolated tracheal smooth muscle in guinea pig.Methods:The effects of these six extractions from Wuhu Decoction were in vitro investigated in the contraction of tracheal strips of the guinea pig trachea.Results: Six extractions from Wuhu-Tang can prevent histamine-induced in vitro bronchoconstriction of guinea pig.Conclusion:The results indicated that these compounds had antiasthmatic effect and might be the base of antiasthmatic effect of Wuhu Decoction. |
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| Keywords: | Wuhu Decoction antiasthmatic effect guinea pig |
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