经皮椎间盘激光减压术的早期病理与影像变化研究

目的 探索经皮腰椎间盘激光减压术(PLDD)术中患者短期内出现不良反应的原因、影响因素及可行的解决方法.方法 用16只杂种犬模拟PLDD,术后不同时相点行CT、MRI检查,观察术后早期病理变化特点.结果 常规组犬早期病理观察见穿刺侧椎间孔处软组织水肿、部分动物出现小片状坏死;抽吸组犬变化较轻微.CT、MRI可清晰显示术后椎间盘及其周围组织的变化.结论 常规方法PLDD术可导致组织的可逆性损伤,使用持续负压抽吸技术可很好地防止术后并发症.CT、MRI能很好监测术后病理变化.

The early pathology and image study of percutaneous laser disc decompression in beagles

Objective To explore the cause, influencing factor and possible solving method of transient adverse reactions during the operation. Methods Sixteen healthy beagles were undergone virtual PLDD. The changes of vertebral discs and the surrounding tissues were observed by high resolution CT and MRI at different periods after the operation, and the same investigation procedure was carried out after the sacrifice of beagles. Results The beagles of the conventional vaporization group occasionally had limb tic and whining in the operations. Pieces of necrosis and edema could be found in the tissues of intervertebral foramen at the paracentetic side. The histological changes in the negative pressure suction group were less than those in the conventional group. Conclusion The reversible damages of the surrounding tissuses were observed in the conventional group and continuing negative pressure suction during the operations can prevent the damages to the surrounding tissues, all of the changes could be clearly displayed by CT and MRI scan.