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Progressive inflammatory lesions of the brain parenchyma in localized scleroderma of the head
Authors:W. Lüer  D. Jöckel  T. Henze  H. I. Schipper
Affiliation:(1) Department of Neurology, Georg-August-Universität, Robert-Koch-Strasse 40, D-3400 Göttingen, Federal Republic of Germany;(2) Department of Neurology, Phillips-Universität, Rudolf-Bultmann-Strasse 8, D-3550 Marburg, Federal Republic of Germany
Abstract:Summary A patient with localized scleroderma of the head, uveitis, and Raynaud's phenomenon presented with generalized seizures, spastic hemiparesis, and local IgG production in the cerebrospinal fluid. Magnetic resonance imaging revealed progressive cortical and subcortical brain parenchymal lesions mainly adjacent to the cutaneous and bony lesions and probably of inflammatory origin.
Keywords:Localized scleroderma  Magnetic resonance imaging  Central nervous system inflammation  Intrathecal IgG production
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