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角膜新生血管治疗的研究进展
引用本文:杨红,薛劲松,蒋沁. 角膜新生血管治疗的研究进展[J]. 国际眼科杂志, 2016, 16(4): 665-669. DOI: 10.3980/j.issn.1672-5123.2016.4.19
作者姓名:杨红  薛劲松  蒋沁
作者单位:南京医科大学附属眼科医院, 中国江苏省南京市,210029
摘    要:角膜新生血管( corneal neovascularization ,CNV)是由维持角膜无血管的平衡因素被破坏,角膜缘的毛细血管侵入无色清亮的角膜组织导致。 CNV是国内较常见的致盲眼病之一,近年来,尽管免疫学、细胞分子生物学和药理学等学科发展让我们对CNV的发病因素及治疗的认识有不少突破,但病因多样缺乏总结,且迄今为止,对CNV的治疗尚无特效疗法。本文将简要阐述CNV的病因、发病机制,着重总结CNV的治疗进展。

关 键 词:角膜新生血管  病因  发病机制  治疗
收稿时间:2015-12-16
修稿时间:2016-03-14

Research advances of the treatments for corneal neovascularization
Hong Yang,Jin-Song Xue and Qin Jiang. Research advances of the treatments for corneal neovascularization[J]. International Eye Science, 2016, 16(4): 665-669. DOI: 10.3980/j.issn.1672-5123.2016.4.19
Authors:Hong Yang  Jin-Song Xue  Qin Jiang
Affiliation:Eye Hospital, Nanjing Medical University, Nanjing 210029,Jiangsu Province, China;Eye Hospital, Nanjing Medical University, Nanjing 210029,Jiangsu Province, China;Eye Hospital, Nanjing Medical University, Nanjing 210029,Jiangsu Province, China
Abstract:Corneal neovascularization(CNV)is caused by the unbalance of corneal avascularity maintaining factors, and then the limbus capillary invades the transparent corneal tissue. CNV is one of the common causes of blindness. In recent years, with the developing of immunology, molecular biology and pharmacology,we have made a lot of breakthroughs about the pathogenesis and treatment of CNV. However, there is no effective medicine and therapy for CNV. In this article we reviewed the pathogenesis, molecular mechanism of CNV, and focus on the progress of therapies.
Keywords:corneal neovascularization   pathogenesis   molecular mechanism   therapy
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