嗜麦芽寡养单胞菌感染分布及耐药性研究

目的了 解我院嗜麦芽寡养单胞菌的临床分布,分析细菌的耐药谱,提高其诊治水平.方法 对经VITEK系统鉴定出162株嗜麦芽寡养单胞菌,进行自动化、纸片扩散法药敏试验,统计分析其感染分布及耐药性变化.结果 在所有临床分离的嗜麦芽寡养单胞菌标本中,以痰液为主（90.1%）,其次为创口分泌物和咽拭子;该菌对大多数抗菌药物耐药,复方新诺明、环丙沙星的耐药率较低,分别为20.4%和22.2%.结论 嗜麦芽寡养单胞菌是重症监护病房（ICU）常见的医院感染致病菌,痰标本的分离率最高;合理使用抗菌药物、减少侵袭性操作、加强耐药性监测,有利于预防及控制医院嗜麦芽寡养单胞菌感染.

Distribution and Drug-resistance of Stenotrophomonas maltophilia

OBJECTIVE To get knowledge of the distribution and drug-resistance of Stenotrophomonas maltophilia in our hospital and improve the level of diagnosis and treatment.METHODS The automatic drug sensitive test and the paper spreads medicine sensitive test were carried on to 162 strains of S.(maltophilia) with the index of the VITEK system.RESULTS In all clinical samples,S. maltophilia isolated from phlegm was the most(90%),then was from secretion and swab.The majority of 162 strains were multidrug resistant.But to the(trimethoprim)-sulfamethoxazole and ciprofloxacin,the drug resistance was low((20.4%) and 22.2%,respectively).CONCLUSIONS S.maltophilia is the prevalent pathogen of nosocomial infection in ICU.And most of it are(isolated) from phlegm.So use antibiotics correctly,(reduce) invasive examinations or treatments and strengthen drug-resistant monitoring,are helpful to prevent and control S.maltophilia nosocomial infection.