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Fungal lung disease
Affiliation:1. Department of Pediatrics, National and Kapodistrian University of Athens, School of Medicine, Aghia Sophia Childrens Hospital, Greece;2. Perelman School of Medicine at the University of Pennsylvania, Attending Physician, Division of Infectious Diseases, The Children’s Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104, United States
Abstract:Fungal lung disease in the paediatric population occurs with distinct features in the immunocompetent, in immunocompromised patients and in people with cystic fibrosis. Pulmonary mycoses are the least prevalent in immunocompetent children, with the most common diseases being the endemic mycoses and Aspergillomas. Filamentous fungi such as Aspergillus and Scedosporium have been isolated with increased frequency in recent years from the respiratory secretions of individuals with cystic fibrosis. Undoubtedly, fungal respiratory infections are encountered with increased frequency and severity in patients with impaired immune systems, such as patients with malignancies, solid organ or bone marrow transplants and immunodeficiencies [1].
Keywords:Immunocompetent  Immunocompromised  Fungus  Cystic fibrosis
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