钛表面掺镓羟基磷灰石涂层的合成和性能表征

目的:钛表面制备含镓羟基磷灰石(Ga-HA)涂层并研究其理化性能。方法:溶胶-凝胶法制备Ga-HA,浸润-提拉法制备涂层并煅烧。SEM检测涂层表面形貌,FTIR、XRD分析其基团结构,拉伸试验检测其结合强度,AAS检测镓、钙离子释放浓度。结果:Ga-HA的结晶度高于HA。体外释放实验结果显示煅烧后涂层钙、镓离子释放量减少。讨论:镓的掺入使HA结晶度增强但未改变其主要晶相结构;镓的掺入有助于减缓涂层的降解,为Ga-HA涂层在骨质疏松患者的临床应用提供了基础。

Fabrication and Characterization of Gallium-containing Hydroxyapatite Coating on Titanium Substrate

Objective: To study the synthesis and characterization of gallium-containing hydroxyapatite coatings. Methods: Gallium-containing hydroxyapatite coatings were prepared by means of sol-gel, which were then deposited on titanium substrates with dip-withdrawal technique. The as-prepared coatings were then calcinated. Surface morphology of the coatings was tested by scanning electron microscope (SEM). The presence of functional groups for coatings was observed by X-ray diffraction spectra (XRD) and Fourier transform infrared spectroscopy spectra (FTIR). The bonding strengths of the samples were performed by pull-out test and the concentrations of Ga3+ and Ca2+ which were released from the coatings were measured by atomic absorption spectrometry (AAS). Results: Compared with HA coatings, the crystallinity of Ga-HA was higher. The concentration of released Ga3+ and Ca2+ decreased after the heat treatment to the coatings. Conclusion: The introduction of Ga increased the crystallinity but little changed the whole structure of HA coatings. The incorporation of Ga decreased the degradation of the coatings. The present study suggested the promising application of Ga-HA coatings.