| 纳米材料在癌症光动力治疗研究中的应用进展 |
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| 引用本文： | 张叶叶,刘俊杰,孙治国,钟延强,邹豪. 纳米材料在癌症光动力治疗研究中的应用进展[J]. 中国医院药学杂志, 2015, 35(21): 1968-1973. DOI: 10.13286/j.cnki.chinhosppharmacyj.2015.21.22 |
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| 作者姓名： | 张叶叶 刘俊杰 孙治国 钟延强 邹豪 |
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| 作者单位： | 中国人民解放军第二军医大学药学院药剂学教研室, 上海 200433 |
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| 基金项目： | 国家自然科学基金项目(编号:30801441);科技部重大新药创制专项(编号:2014ZX09J14107-01B) |
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| 摘 要： | 纳米材料以其明确的大小、形状、组成和表面能等性能为生物分析、生物成像和治疗提供了多模式、多功能的平台。本文重点综述了多种纳米技术在光动力疗法治疗癌症方面的应用进展,包括上转换纳米粒、量子点、纳米金、碳纳米材料、二氧化硅纳米粒、脂质体和胶束纳米材料,对各种纳米材料的特点以及近些年来相关研究和发展情况进行了评述。
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| 关 键 词： | 纳米材料 光动力疗法 癌症 |
| 收稿时间： | 2014-10-10 |
Advances in application of nanomaterials for photodynamic therapy against cancer |
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| ZHANG Ye-ye,LIU Jun-jie,SUN Zhi-guo,ZHONG Yan-qiang,ZOU Hao. Advances in application of nanomaterials for photodynamic therapy against cancer[J]. Chinese Journal of Hospital Pharmacy, 2015, 35(21): 1968-1973. DOI: 10.13286/j.cnki.chinhosppharmacyj.2015.21.22 |
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| Authors: | ZHANG Ye-ye LIU Jun-jie SUN Zhi-guo ZHONG Yan-qiang ZOU Hao |
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| Affiliation: | Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Nanomaterials with well-defined size,shape,composition and surface functionalities offer a platform with multi-mode and multifunction for bioanalysis,bioimaging and therapies.Herein,we mainly sum up applications of various nanotechnologies for photodynamic therapy against cancer,including upconversion nanoparticles,quantum dots,gold nanoparticles,carbon nanomaterials,silica nanoparticles,liposomes and micelles,and their characteristics.Related researches and developments in recent years are reviewed. |
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| Keywords: | nanomaterials photodynamic therapy cancer |
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