结直肠癌肝转移的治疗进展

结直肠癌的发病率和死亡率逐年上升,肝转移是主要死因。本文阐述了目前临床上使用较多的治疗方式及进展。分为系统性治疗,包括了新辅助化疗、转化治疗和分子靶向治疗;及局部治疗,包括手术切除、放射治疗、射频消融及介入治疗等。各种治疗手段各有优缺点,多学科综合治疗团队模式的推广,将为结直肠癌肝转移患者制定出较适合的方案,实现个体化治疗。

Treatment progression in colorectal cancer liver metastasis

Colorectal cancer is one of the most common gastrointestinal carcinomas, and the incidence and mortality rates are continually increasing worldwide. The main cause of death is liver metastasis. This article elaborates the current clinical treatments and recent advance. Those can be divided into two main treatments: the systemic treatments include neoadjuvant chemotherapy, conversion chemotherapy and molecular targeted therapy; Local treatments include surgery, radiation therapy, radiofrequency ablation and interventional treatment, etc. Each treatment has its advantages and disadvantages. Multidisciplinary team would develop a more suitable scheme for patients with liver metastases from colorectal cancer and realize personalized treatment .