经直肠常规超声联合超声造影诊断前列腺癌的价值

目的 探讨经直肠常规超声检查或联合超声造影检查在前列腺癌诊断中的应用价值和意义。方法 选取我院疑似前列腺癌的70例男性患者，均先行经直肠常规超声检查后再行经直肠超声造影检查，比较分析经直肠常规超声检查（常规法）或经直肠常规超声检查后再行经直肠超声造影检查（联合法）诊断前列腺癌的灵敏性、特异性、阳性预测值、阴性预测值及病理检查符合率，并以病理活检为对照。结果 病理活检阳性率为62.9%。常规法正确诊断前列腺癌21例，联合法正确诊断前列腺癌37例。常规法与联合法诊断前列腺癌的灵敏性、特异性、阳性预测值、阴性预测值及病理检查符合率分别为47.7% vs 84.1%、53.8% vs 69.2%、63.6%  vs 82.2%、 37.8% vs 72.0%及50.0% vs 78.6%，二者比较的差异均有统计学意义（P均＜0.05）。结论 与经直肠常规超声检查比较，联合经直肠超声造影检查对前列腺癌诊断有较高的灵敏性、特异性、阳性预测值、阴性预测值及病理检查符合率，具有更高的诊断价值，值得临床推广应用。

The value of contrast-enhanced combined routine transrectal ultrasound in the diagnosis of prostate cancer

Objective To determine the value of  contrast-enhanced and routine transrectal ultrasound combination in the diagnosis of prostate cancer. Method A total of 70 men with suspected prostate cancer were examined by both routine and contrast-enhanced transrectal ultrasound at our hospital. Diagnosis was confirmed by prostate biopsy. Result The pathological positive rate was 62.9%. A total of 37 patients were diagnosed with prostate cancer by contrast-enhanced combined routine transrectal ultrasound，while 21 were diagnosed with prostate cancer by routine transrectal ultrasound. Significantly different values of diagnostic performance parameters were obtained for the contrast-enhanced combined routine technique vs. the routine technique（all P＜0.05）：sensitivity，84.1% vs 47.7%；specificity，69.2% vs 53.8%；positive predictive value，82.2% vs 63.6%；negative predictive value，72.0% vs 37.8%；and pathological coincidence rate，78.6% vs 50.0%. Conclusion Contrast-enhanced combined routine transrectal ultrasound shows higher diagnostic performance than routine transrectal ultrasound for diagnosing prostate cancer.