| 乳牙牙髓干细胞的研究进展 |
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| 引用本文： | 李思洁,赵玮. 乳牙牙髓干细胞的研究进展[J]. 中华口腔医学研究杂志(电子版), 2016, 10(6): 421-424. DOI: 10.3877/cma.j.issn.1674-1366.2016.06.010 |
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| 作者姓名： | 李思洁 赵玮 |
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| 作者单位： | 1. 510055 广州，中山大学光华口腔医学院·附属口腔医院，广东省口腔医学重点实验室 |
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| 基金项目： | 国家自然科学基金(81472526); 广东省自然科学基金(2014A030313126); 广州市科技计划(201609010015) |
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| 摘 要： | 乳牙牙髓干细胞（SHED）来源于脱落的乳牙牙髓，具有较强的增殖能力、自我更新能力、多向分化潜能，而且乳牙为生物废弃物，符合伦理要求，所以渐渐成为干细胞领域研究的新热点。本文就SHED的生物学特征、培养方法、鉴定方法、多向分化潜能及其在疾病治疗中应用的研究进展作一综述。
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| 关 键 词： | 牙，乳 牙髓 干细胞 细胞分化 生物学 |
| 收稿时间： | 2016-10-09 |
Research progress on the stem cells isolated from exfoliated deciduous teeth |
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| Sijie Li,Wei Zhao. Research progress on the stem cells isolated from exfoliated deciduous teeth[J]. Chinese Journal of Stomatological Research(Electronic Version), 2016, 10(6): 421-424. DOI: 10.3877/cma.j.issn.1674-1366.2016.06.010 |
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| Authors: | Sijie Li Wei Zhao |
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| Affiliation: | 1. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China |
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| Abstract: | Stem cells from human exfoliated deciduous teeth (SHED) mainly come from exfoliated deciduous teeth. They possess the properties of high proliferation, self-renewal and multiple differentiations potential. Furthermore, deciduous teeth, a biological disposal of waste, conform to ethical concerns. Therefore, SHED gradually become a focus in stem cell research. This review highlights recent advance of the biology characteristic, culture methods, identification methods, multiple differentiation potential of SHED and the application of SHED in the treatment. |
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| Keywords: | Teeth deciduous Dental pulp Stem cells Cell differentiation Biology |
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