| 嗜酸细胞性慢性鼻-鼻窦炎嗅觉障碍与嗜酸性粒细胞的关系 |
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| 引用本文： | 赵松花,孙绍辉,陈娜,朱奇,陈禹,佘文煜,刘辉. 嗜酸细胞性慢性鼻-鼻窦炎嗅觉障碍与嗜酸性粒细胞的关系[J]. 武警医学, 2015, 26(4): 350-352 |
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| 作者姓名： | 赵松花 孙绍辉 陈娜 朱奇 陈禹 佘文煜 刘辉 |
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| 作者单位： | 1.130052 长春,武警吉林总队医院耳鼻咽喉科;2.100730,首都医科大学附属北京同仁医院耳鼻咽喉头颈外科;3.130021 长春,吉林省人民医院耳鼻咽喉科 |
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| 摘 要： | 目的 探讨嗜酸细胞性慢性鼻-鼻窦炎(eosinophilic chronic sinusitis, ECRS)中嗅区黏膜嗜酸性粒细胞(eosinophills, EOS)浸润水平与嗅觉障碍间的关系。方法 选择接受鼻内镜手术治疗的ECRS患者45例,术前行T&T嗅觉检查法嗅觉功能检测,术中取嗅区黏膜活检,HE染色,计数黏膜上皮下EOS,计算Spearman’s Rank 相关系数r。结果 45例ECRS患者嗅觉功能评分为2.3±1.9,嗅区黏膜上皮下EOS计数为(253±102)/HP,Spearman’s Rank 相关系数r=0.68(P<0.01)。结论 ECRS患者嗅觉功能下降与嗅区黏膜EOS浸润存在明显相关性。
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| 关 键 词： | 嗜酸细胞性慢性鼻-鼻窦炎 鼻黏膜 嗅觉障碍 嗜酸性粒细胞 |
| 收稿时间： | 2014-12-12 |
Relationship between olfactory dysfunction and eosinophil counts in eosinophilic chronic sinusitis |
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| ZHAO Songhua,SUN Shaohui,CHEN Na,ZHU Qi,CHEN Yu,SHE Wenyu,LIU Hui. Relationship between olfactory dysfunction and eosinophil counts in eosinophilic chronic sinusitis[J]. Medical Journal of the Chinese People's Armed Police Forces, 2015, 26(4): 350-352 |
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| Authors: | ZHAO Songhua SUN Shaohui CHEN Na ZHU Qi CHEN Yu SHE Wenyu LIU Hui |
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| Affiliation: | 1. Department of Otolaryngology, Jilin Provincial Corps Hospital, Chinese People’s Armed Police Forces, Changchun 130052,China;2.Department of Otolaryngology Head and Neak Surgery, Beijing Tongren Hospital,Capital Medical University, Beijing 100730,China;3.Department of Otolaryngology, Jilin Provincial People’s Hospital, Changchun 130021, China |
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| Abstract: | Objective To study the relationship between olfactory dysfunction and eosinophila in eosinophilic chronic rhinosinusitis. Methods 45 patients with ECRS, 29 males and 16 females, age range 23 to 65 with average 33.7. Olfactory function was evaluated by T&T method, mucosal tissue specimens were collected at the time of surgery and eosinophil counts were used to identify histologic feature. Spearman’s rank correlation was assessed. Results The olfactory dysfunction was observed in ECRS patients with 2.3±1.9 and correlated with eosinophil counts (253±102)/HP with(r=0.68,P<0.01). Conclusions The olfactory dysfunction in ECRS is correlated with eosinophil counts in olfactory nasal mucosa. |
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| Keywords: | eosinophilic chronic sinusitis nasal mucosa olfactory dysfunction eosinophills |
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