百草枯中毒进行性肺损害HRCT表现与临床预后的关系

目的 探讨百草枯中毒进行性肺损害HRCT表现与临床预后的关系。方法 结合相关文献,回顾性分析5例百草枯中毒死亡病例的临床及进行性肺损害HRCT表现。结果 中毒早期(1～7 d)HRCT表现肺纹理增粗、紊乱、模糊,局部肺叶透光度减低,胸膜下见磨玻璃影及少许实变影。中毒中期(8～14 d)HRCT表现肺纹理进行性增粗、紊乱,磨玻璃影及实变影范围增大,气胸、纵膈及胸壁皮下气肿。中毒后期(≥15 d)HRCT表现肺实质性病变、肺间质性病变、支气管扩张、胸腔积液伴肝脾肾肿大。结论 百草枯中毒进行性肺损害HRCT表现与临床病情发展转归具有一致性,对临床治疗和预后判断有很高的应用价值。

HRCT manifestations and clinical prognosis of lung injury induced by paraquat poisoning

Objective To investigate the relationship between HRCT manifestations and clinical prognosis of lung injury induced by paraquat poisoning. Methods Five cases of paraquat poisoning were retrospectively analyzed the clinical and progressive lung injury HRCT performance combined with related literature. Resutls In the early period (1~7d): HRCT showed lung markings thickening, disorder, blurred, local lobular transmittance reduced, the ground-glass below the pleura and a little solid shadow observed. In the middle period (8~14d): HRCT showed pulmonary veins progressive thickening, disorders, ground glass and solid shadow area increased, pneumothorax, mediastinal and chest wall subcutaneous emphysema. The late poisoning (more than 15d): the performance of pulmonary parenchymal lesions, interstitial lung disease, bronchiectasis, pleural effusion, with hepatosplenomegaly. Conclusion Paraquat poisoning of HRCT performance and prognosis of clinical disease outcome is consistent, and the clinical treatment and prognosis have a high application value.