经门静脉栓塞化疗术与经肝动脉化疗栓塞术治疗结直肠癌肝转移瘤临床效果比较

目的：研究经门静脉栓塞化疗术（PVCE）治疗结直肠癌肝转移瘤的疗效、生存期及并发症。 方法：80例明确诊断的结直肠癌肝转移瘤患者，分成两组，PVCE组40例，行PVCE术。另外40例行经肝动脉化疗栓塞术（TACE组）。 结果：PVCE组临床有效率为82.5%，高于TACE组的55.0%，差异有统计学意义。PVCE组40例患者6、12、24个月的生存率分别为：92.5%、62.5%及40.0%，TACE组40例患者6、12、24个月的生存率分别为75.0%、52.5%及22.5%。PVCE组生存情况优于TACE组。 结论：经门静脉介入治疗结直肠癌肝转移瘤疗效确切，生存期优于经肝动脉介入治疗。

A clinical comparison of interventional strategies of PVCE and TACE on hepatic metastasis from colorectal cancer

Objective:To study the therapeutic effect, survival time and complications of transcatheter portal vein chemoembolization (PVCE) in the treatment of liver metastases from colorectal cancer. Methods:80 cases of colorectal cancer with pathologically confirmed liver metastases were collected and randomly divided into two groups. In the treatment group, 40 patients underwent PVCE while in the control group 40 patients underwent TACE. Results:The rate of CR+PR is 82.5% in PVCE group and 55.0% in TACE group. It also showed a statistical significance of t 6, 12, and 24 months survivals as 92.5%, 62.5% and 40.0% in PVCE group, while that in the TACE group were 75.0%, 52.5% and 22.5%, respectively. Conclusions:In treating hepatic metastasis from colorectal cancer, the PVCE has a better therapeutic effect with a higher survival rate and longer survival time in comparison with TACE.