| 山茶花总黄酮对血小板聚集和实验性血栓形成的影响 |
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| 引用本文： | 袁丽萍,范丽,董六一,郭岩,赵维中,陈志武. 山茶花总黄酮对血小板聚集和实验性血栓形成的影响[J]. 安徽医科大学学报, 2004, 39(2): 142-144 |
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| 作者姓名： | 袁丽萍 范丽 董六一 郭岩 赵维中 陈志武 |
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| 作者单位： | 安徽医科大学药理学教研室,合肥,230032 |
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| 摘 要： | 目的研究山茶花总黄酮(TFC)对血小板聚集和实验性血栓形成的影响.方法采用体外血小板聚集实验法观察TFC对血小板聚集的影响;采用大鼠动静脉血栓旁路法观察TFC对实验性血栓形成的影响.结果 TFC 1.0、0.5、0.25 g/L能明显对抗胶原诱导的血小板聚集;TFC 60、 30 mg/kg能明显减轻大鼠血栓的湿重.结论 TFC具有明显的抗血小板聚集、抑制血栓形成的作用.
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| 关 键 词： | 山茶科 血小板聚集 血栓形成 |
| 文章编号： | 1000-1492(2004)02-0142-03 |
| 修稿时间： | 2003-08-01 |
Effects of total flavone of C on platelet aggregation and experimental thrombosis |
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| Yuan Liping,Fan Li,Dong Liuyi et al. Effects of total flavone of C on platelet aggregation and experimental thrombosis[J]. Acta Universitis Medicinalis Anhui, 2004, 39(2): 142-144 |
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| Authors: | Yuan Liping Fan Li Dong Liuyi et al |
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| Abstract: | Objective To study the effects of total flavone of C(TFC) on platelet aggregation and experimental thrombosis. Methods Inhibition rates of platelet aggregation for TFC in vitro were determined by the model of platelet aggregation induced by coll;inhibition rates of experimental thrombosis for TFC were measured by the model of A-V thrombosis passby. Results TFC 1.0,0.5,0.25 g/L had magnificent effect on inhibition of platelet aggregation;TFC 60,30 mg/kg decreased the wet weight of thrombosis obviously compared with the control group. Conclusion TFC exhibits inhibition of platelet aggregation and antithrombosis effects. |
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| Keywords: | theaceae platelet aggregation thrombosis |
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