| 高效液相色谱法测定利咽含片中绿原酸的含量 |
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| 引用本文： | 宋卫中,刘蔚. 高效液相色谱法测定利咽含片中绿原酸的含量[J]. 河南大学学报(医学版), 2005, 24(3): 23-24 |
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| 作者姓名： | 宋卫中 刘蔚 |
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| 作者单位： | 河南大学成人教育学院,河南,开封,475001;河南大学东京医院,药剂科,河南,开封,475000 |
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| 摘 要： | 目的:研究利咽含片中绿原酸的含量测定。方法:采用高效液相色谱法进行测定。ODS柱,甲醇-水-冰醋酸(24∶75∶1)为流动相,流量为0.9ml/min,检测波长为329nm。结果:绿原酸在0.130μg~0.650μg之间线性关系良好,相关系数R=0.9994,回收率为100.02%,RSD为1.29%。结论:本法灵敏、简便、准确,可用于本制剂的测定和质量控制指标。
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| 关 键 词： | 利咽含片 绿原酸 高效液相色谱法 |
| 文章编号： | 1672-7606(2005)03-0023-02 |
| 收稿时间： | 2005-04-28 |
| 修稿时间： | 2005-04-28 |
Determination of the contents of chlorogenic acid in LI YAN Lozenge with HPLC |
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| SONG Wei-zhong,LIU Wei. Determination of the contents of chlorogenic acid in LI YAN Lozenge with HPLC[J]. Journal of Henan University, 2005, 24(3): 23-24 |
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| Authors: | SONG Wei-zhong LIU Wei |
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| Abstract: | Objective: To study the contents of chlorogenic acid in LI YAN Lozenge with HPLC.Methods: The contents contents of chlorogenic acid in LI YAN Lozenge were determined with HPLC, HPLC column was ODS, the mobile was methanol-water-glacial acetic acid((24∶75∶1)),the flow rate was 0.9 ml/min,the detection wavelength was at 329nm. Results: The linear range of chlorogenic acid was in the range of 0.130～0.650μg,r=0.9994,and its average recovery was 100.02%(RSD=1.29%).Conclusion: It is sensitive, simple, accurate, so HPLC can be used for the determination of preparations and the standards of the quality control. |
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| Keywords: | LI YAN Lozenge chlorogenic acid HPLC |
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