氩离子凝固术治疗巴瑞特食管的临床观察

目的探讨内镜下氩离子凝固术(APC)治疗Barrett食管(BE)的临床疗效。方法选择21003年5月至2004年2月经内镜检查及病理组织学检查诊断的BE患者22例，在内镜下行APC治疗，氩离子凝固治疗单次启动延续时间及启动次数视病灶大小、数目情况而定，一般以内镜下整个病灶凝固为止，所有病例1～3个月内复查内镜。结果22例BE患者中1例失访，1例未到复查时间，其余20例BE患者至复查时17例(85％)胃镜下未见复发，2例在原来部位有散在BE上皮残留，1例在其他部位有新BE上皮生长。结论APC是经内镜非接触性治疗BE的新方法，操作方便，短期疗效较好。

Clinical effect of argon plasma coagulation in endoscopic treatment of Barrett esophagus

Objective To explore the clinical effect of the argon plasma coagulation(APC) in the endoscopic treatment of Barrett esophagus(BE). Methods After the diagnosis as BE with endoscopy and pathohistolog y, 22 outpatients through May 2003 to Feb 2004 were treated with APC. The treatm ent time and operating times depended on the size and the number of the lesions. All the cases were re-checked by endoscopy in 1-3 months after APC. Results In 22 patients, one failed to be followed-up, one was not up to the follow-up time, and complete squamous reepithelialization was observ ed in 17 patients (85%), whereas remnant islands of columnar epithelium in the o riginal places were observed in 2 patients. Small new islands of columnar epithe lium in other places were observed in 1 patient during follow-up. Conclusion The clinical experience shows APC is a new non-touched endoscopic technique and it is a rather effective and convenient method in trea ting BE.