涎腺肌上皮瘤的临床病理分型和免疫组化研究

对从１８７３例涎腺肿瘤复查后确诊的４３例涎腺肌上皮瘤进行了临床病理学和免疫组化研究，结果显示：该瘤的发病率约占涎腺肿瘤的２．３％，好发于腮腺（４８．８４％）和腭腮（４１．８６％），该瘤在病理上可分为五型：即上皮细胞型，梭形细胞型，浆细胞细胞型，透明细胞型和混合细胞型，其实质细胞－肿瘤性肌上皮细胞为一个连续变化的瘤细胞谱。各种形态的瘤细胞可以互相转化；免疫组化ＣＫ－１８，ａｃｔｉｎ染色显示上述各型瘤

Clinical Pathological Classification and Immunohischemistry Study of Myoepithelioma of Salivary Gland

43 cases myoepithlioma of salivary gland , which were confirmed through histological reexamination of the 1873 cases of salivary gland tumors, were studied with clinical pathological and immunohistochemical method. The results showed that this tumor' s morbidity constituted about 2. 3% of the salivary gland tumor. The tumor usually occurred in parotid gland (48. 84%) and palatine glands (41. 86%). It could be classified into five types on the basis of histopathology; Epithelial cell, Spindle cell ,Plasmacytoid cell, Clear cell and Mixed cell. Those parenchymal cells , neoplastic myoepithelial cell, are a continuous oncocyte pedigree which appearance of oncocytes might chang with each other. The results of CK-18 and Actin immunohistochemistry indicated various degree of positive expression in five types. It is important that various oncocytes were recognized. Combination use of CK-18 and Actin antibodies is an authetic method to improve confirmed diagnosis rate of the tumor