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An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris |
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| Authors: | J L Lesher D K Chalker J G Smith L C Guenther C N Ellis J J Voorhees A R Shalita H C Klauda |
| Affiliation: | Departments of Pediatrics and Dermatology University of Miami School of Medicine Miami, FL 33101;Department of Pediatrics Montefiore Medical Center Albert Einstein College of Medicine Director, North Bronx Child Protective Service Program Bronx, NY 10467 |
| Abstract: | Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients. |
| Keywords: | Reprint requests to: Dr. Jack L. Lesher Jr Department of Dermatology Medical College of Georgia Augusta GA 30912. |
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