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卡介苗与羟基喜树碱膀胱灌注预防肿瘤复发Meta分析比较
引用本文:闫鸣,陈晓,郑志学,杨旭东. 卡介苗与羟基喜树碱膀胱灌注预防肿瘤复发Meta分析比较[J]. 现代泌尿外科杂志, 2008, 13(6): 450-452
作者姓名:闫鸣  陈晓  郑志学  杨旭东
作者单位:首都医科大学附属北京朝阳医院泌尿外科,北京,100020
摘    要:目的评价膀胱灌注卡介苗(BCG)与羟基喜树碱(HCPT)预防国人膀胱肿瘤术后复发的疗效和副作用。方法检索国内已公开发表的关于BCG与HCPT膀胱灌注治疗国人膀胱肿瘤术后复发的研究资料,并应用Revman4.2软件进行数据处理和分析。结杲共有10个研究符合标准被纳人,Meta分析结果提示BCG与HCPT膀胱灌注都可降低膀胱肿瘤复发风险;9个研究报道了主要副作用膀胱刺激症/化学性膀胱炎的比较,Meta分析结果提示HCPT膀胱灌注所致膀胱刺激症/化学性膀胱炎发生率较低。结论与BCG相比,HCPT不仅能有效降低膀胱肿瘤术后复发,而且副反应更低。

关 键 词:膀胱肿瘤  膀胱灌注  系统评价

Meta-analysis of intravesical bacillus calmette guerin and hydroxycamptochecine on recurrence of Chinese bladder carcinoma
Yan Ming,Chen Xiao,Zheng Zhixue,Yang Xudong. Meta-analysis of intravesical bacillus calmette guerin and hydroxycamptochecine on recurrence of Chinese bladder carcinoma[J]. Journal of MOdern Urology, 2008, 13(6): 450-452
Authors:Yan Ming  Chen Xiao  Zheng Zhixue  Yang Xudong
Affiliation:Yan Ming,Chen Xiao,Zheng Zhixue,Yang Xudong(Department of Urology,Beijing Chaoyang Hospital Affiliated to Capital Medical University,Beijing 100020,China)
Abstract:Objective To assess the efficacy and treatment-induced side effects of intravesical bacillus calmette-guerin(BCG) and Hydroxycamptochecine(HCPT) on recurrence of Chinese bladder carcinoma.Methods Published studies on intravesical BCG and HCPT for bladder carcinoma of Chinese people were reviewed.Data were extracted from each identified paper and Revman 4.2 software was used for statistical analysis.Results Totally 10 trials were eligible to the inclusion criteria.Pooling data of a meta-analysis indicated th...
Keywords:bladder carcinoma  intravesical  meta-analysis  
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