Voluven, a new colloid solution |
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| Authors: | Mizzi Anna Tran Thanh Karlnoski Rachel Anderson Ashley Mangar Devanand Camporesi Enrico M |
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| Institution: | aDepartment of Cardiothoracic and Vascular Anesthesia, San Raffaele Hospital, “Vita e Salute” University, Milan, Italy;bFlorida Gulf-to-Bay Anesthesiology Associates, 1 Tampa General Circle Suite A327, Tampa, FL 33606, USA;cDepartment of Plastic Surgery, University of South Florida, Tampa, FL, USA;dDepartment of Surgery, University of South Florida, Tampa, FL, USA;eDepartment of Anesthesiology, University of South Florida, Tampa, FL, USA |
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| Abstract: | Hydroxyethyl starch (HES) 130/0.4 (Voluven, Fresenius/Hospira, Germany) is indicated for the treatment and prophylaxis of hypovolemia. As the Voluven molecule is smaller than those of other available hydroxyethyl starch products, it is associated with less plasma accumulation and can be safely used in patients with renal impairment. Previous studies have demonstrated that Voluven has comparable effects on volume expansion and hemodynamics as other available HES products. Voluven is also associated with fewer effects on coagulation and may be an acceptable alternative to albumin for volume expansion in situations in which other starches are contraindicated secondary to risk of coagulopathy. |
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| Keywords: | Hydroxyethyl starch Voluven Colloids Crystalloids |
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