Subacute cutaneous lupus erythematosus associated with leflunomide |
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| Authors: | Elias Anthony R Tam Christine C David-Bajar Kathleen M |
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| Affiliation: | Dermatology Clinic, US Army Medical Department Activity, Fort Drum, New York 13602, USA. anthony.elias@us.army.mil |
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| Abstract: | A skin eruption consistent with subacute cutaneous lupus erythematosus (SCLE) occurred in a patient taking leflunomide for rheumatoid arthritis. The eruption resolved after discontinuation of the medication. Suppression of tumor necrosis factor (TNF)-effector mechanisms by leflunomide may have played a role in the pathogenesis of this disorder. |
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