Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice

Authors:	Xiao?Su Mark?R.?Looney Hang??Su Jae?Woo?Lee Yuanlin?Song Michael?A.?Matthay

Affiliation:	(1) Cardiovascular Research Institute, University of California, San Francisco, HSW 825, 505 Parnassus AVE, San Francisco, CA 94143-0130, USA;(2) Department of Medicine, University of California, San Francisco, San Francisco, CA, USA;(3) Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA, USA

Abstract:	Objective and design Cystic fibrosis transmembrane conductance regulator (CFTR) regulates infection and inflammation. In this study, we investigated whether a lack of functional CFTR in neutrophils would promote lipopolysaccharide (LPS)-induced lung inflammation and injury.

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