Utility of the WHO‐five well‐being index as a screening tool for depression in Parkinson's disease |
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| Authors: | Christine B. Schneider MD Maximilian Pilhatsch MD Martina Rifati Wolfgang H. Jost MD Franziska Wodarz Georg Ebersbach MD Daniela Djundja Gerd Fuchs MD Arne Gies Per Odin MD Gerd Reifschneider MD Martin Wolz MD Antonia Bottesi MD Michael Bauer MD PhD Heinz Reichmann PhD Alexander Storch MD |
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| Affiliation: | 1. Department of Neurology, Dresden University of Technology, Dresden, Germany;2. Department of Psychiatry and Psychotherapy, Dresden University of Technology, Dresden, Germany;3. Department of Neurology, Deutsche Klinik für Diagnostik, Wiesbaden, Germany;4. Movement Disorders Clinic, Beelitz‐Heilst?tten, Germany;5. Parkinson Clinic Wolfach, Wolfach, Germany;6. Department of Neurology, Zentralkrankenhaus Reinkenheide, Bremerhaven, Germany;7. Neuro Centrum Odenwald, Erbach, Germany |
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| Abstract: | Beck depression inventory (BDI‐1A) is the gold standard screening tool for Parkinson's disease (PD) depression, but as a result of its complexity, it is of limited suitability as a quick and easy screening device. We, therefore, validate the 5‐item WHO‐Five Well‐being Index (WHO‐5) as a screening tool for PD depression. Two hundred thirteen of 215 recruited PD patients (99.1%) completed the WHO‐5. Receiver operating characteristic plots were used to calculate sensitivity/specificity for all cut‐off scores for the detection of depression and combined depression/dysthymia as assessed by an independent investigator using the Mini International Neuropsychiatric Interview (MINI). Internal consistency of the WHO‐5 was good (Cronbach's α = 0.83). WHO‐5 showed high validity with adequate detection of depression without differences in the validity indices compared to BDI‐1A (P = 0.234). The optimal cut‐off value for detection of depression was 12 of 13 points. WHO‐5 is a useful, brief, and easy instrument for identifying PD subjects with depression in daily practice. © 2010 Movement Disorder Society |
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| Keywords: | Parkinson's disease depression WHO‐Five Well‐being Index validity screening BDI‐1A |
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