T2‐weighted 3D fast spin echo imaging with water–fat separation in a single acquisition |
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| Authors: | Ananth J. Madhuranthakam PhD Huanzhou Yu PhD Ann Shimakawa MS Reed F. Busse PhD Martin P. Smith MD Scott B. Reeder MD PhD Neil M. Rofsky MD Jean H. Brittain PhD Charles A. McKenzie PhD |
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| Affiliation: | 1. Applied Science Lab, GE Healthcare, Boston, Massachusetts, USA;2. Applied Science Lab, GE Healthcare, Menlo Park, California, USA;3. Applied Science Lab, GE Healthcare, Madison, Wisconsin, USA;4. Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA;5. Departments of Radiology, Medical Physics, Biomedical Engineering and Medicine, University of Wisconsin, Madison, Wisconsin, USA;6. Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada |
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| Abstract: | Purpose: To develop a robust 3D fast spin echo (FSE) T2‐weighted imaging method with uniform water and fat separation in a single acquisition, amenable to high‐quality multiplanar reformations. Materials and Methods: The Iterative Decomposition of water and fat with Echo Asymmetry and Least squares estimation (IDEAL) method was integrated with modulated refocusing flip angle 3D‐FSE. Echoes required for IDEAL processing were acquired by shifting the readout gradient with respect to the Carr‐Purcell‐Meiboom‐Gill echo. To reduce the scan time, an alternative data acquisition using two gradient echoes per repetition was implemented. Using the latter approach, a total of four gradient echoes were acquired in two repetitions and used in the modified IDEAL reconstruction. Results: 3D‐FSE T2‐weighted images with uniform water–fat separation were successfully acquired in various anatomies including breast, abdomen, knee, and ankle in clinically feasible scan times, ranging from 5:30–8:30 minutes. Using water‐only and fat‐only images, in‐phase and out‐of‐phase images were reconstructed. Conclusion: 3D‐FSE‐IDEAL provides volumetric T2‐weighted images with uniform water and fat separation in a single acquisition. High‐resolution images with multiple contrasts can be reformatted to any orientation from a single acquisition. This could potentially replace 2D‐FSE acquisitions with and without fat suppression and in multiple planes, thus improving overall imaging efficiency. J. Magn. Reson. Imaging 2010;32:745–751. © 2010 Wiley‐Liss, Inc. |
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| Keywords: | 3D FSE 3D T2‐weighted imaging water‐fat separation IDEAL fat suppression |
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