Effect of maximal voluntary contraction on the amplitude of the compound muscle action potential: Implications for the interpolated twitch technique |
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| Authors: | Michael J. Berger BSc Bradley V. Watson BSc Timothy J. Doherty MD PhD |
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| Affiliation: | 1. Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada;2. Department of Clinical Neurological Sciences, London Health Sciences Centre London, Ontario, Canada;3. Department of Physical Medicine and Rehabilitation, London Health Sciences Centre, 339 Windermere Road, London, Ontario N6A 5A5, Canada |
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| Abstract: | The compound muscle action potential (MMAX) during a maximal voluntary contraction (MVC) may be measured to determine if the motor nerve has been supramaximally stimulated during the interpolated twitch technique (ITT). Ten males performed isometric knee extension MVCs. MMAX for the vastus medialis was recorded during MVC and rest. To examine the effect of stimulating electrode movement, the MMAX of the thenar group and antidromic sensory nerve action potentials (SNAPs) to the third digit were recorded in a separate experiment. MMAX during MVC was reduced by 18% (P < 0.0001) and 43% (p < 0.0001) for the quadriceps and thenar group, respectively. The SNAP amplitude was not different between rest and MVC (P = 0.18). Reduction of MMAX during MVC suggests that some motor axons are refractory and unable to respond to a superimposed maximal stimulus. These results have implications for the sensitivity of the interpolated twitch technique. Muscle Nerve, 2010 |
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| Keywords: | interpolated twitch technique quadriceps muscle weakness voluntary activation compound muscle action potential sensory nerve action potential |
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