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Thymidine phosphorylase to dihydropyrimidine dehydrogenase ratio as a predictive factor of response to preoperative chemoradiation with capecitabine in patients with advanced rectal cancer
Authors:C.S. Boskos MD  C. Liacos MSc  D. Korkolis PhD  K. Aygerinos PhD  I. Lamproglou MSc  E. Terpos PhD  E. Stoupa  G. Baltatzis PhD  K. Beroukas PhD  P. Papasavvas PhD  M.A. Dimopoulos PhD  A. Bamias PhD
Affiliation:1. 1st Radiation Oncology Department, “Agios Savvas” Anticancer Institute, Athens, Greece;2. Clinical Oncology Department, 251 General Hellenic Airforce Hospital, Athens, Greece;3. Clinical Therapeutics Department, Medical School, University of Athens, Greece;4. 1st Surgical Department, “Agios Savvas” Anticancer Institute, Athens, Greece;5. 1st Surgical Department, Hospital “Agia Olga”, Athens, Greece;6. Radiation Oncology Department, Pitie‐Salpetriere, Paris, France;7. Medical Research Department, 251 General Hellenic Airforce Hospital, Athens, Greece;8. Electron‐Microscopy and Cell Biology Department, Research Center “G. Papanikolaou”, “Agios Savvas” Anticancer Institute, Athens, Greece
Abstract:
Keywords:capecitabine  chemoradiation  rectal cancer  thymidine phosphorylase (TP)  dihydropyrimidine dehydrogenase (DPD)
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