储水桶对血液透析用水中内毒素含量的影响

目的:研究储水桶对血液透析用水中内毒素含量的影响。方法:以上海市36家医院的血液透析中心为调查对象,采用显色基质法对各血液透析中心2010年11月—2012年10月透析用水中的内毒素含量进行检测。结果:36家血液透析中心2年内送检的透析用水标本数为2694份,其中2348份标本(87.16%)中的内毒素含量0.1 EU/mL,260份标本(9.65%)中的内毒素含量为0.1~0.5 EU/mL,其余86份标本(3.19%)中的内毒素含量0.5 EU/mL。36家透析中心中,使用储水桶的有19家,另17家未使用储水桶,使用储水桶的透析中心的透析用水中内毒素含量高于未使用储水桶的透析中心,差异有统计学意义(P0.05)。结论:使用储水桶可显著增加血液透析用水中内毒素含量,应加强对储水设备的管理。

Influence of Water Tank on Endotoxin Content in Hemodialysis Fluid

Objective：To investigate the influence of water tank on endotoxin（ET）content in hemodialysis fluid.Methods：Specimens of hemodialysis fluid were collected from36 hemodialysis centers in Shanghai from Nov 2010 to Oct 2012,and the ET content in hemodialysis fluid were detected by chromogenic substrate method.Results：A total of 2694 samples have been obtained from36 hemodialysis centers during the 2 years＇ period.The contents of ET below0.1 EU/mL were detected in2348（87.16%）samples,between 0.1 EU/mL and 0.5 EU/mL in 260（9.65%）samples,and above 0.5 EU/mL in 86（3.19%）samples.Water tanks were used in19 of the 36 hemodialysis centers.ET contents of hemodialysis fluid in the hemodialysis centers which used water tanks were higher than those didn＇t use water tanks,and the difference showed statistical significance（P〈0.05）.Conclusion：The usage of water tank could significantly increase the ET content in hemodialysis fluid.Monitoring of water storage equipment should be strengthened.