序贯疗法与三联疗法治疗幽门螺杆菌性消化性溃疡疗效分析

目的：分析序贯疗法与三联疗法治疗幽门螺杆菌性消化性溃疡的治疗效果。方法选择我院近1年来82例幽门螺杆菌性消化性溃疡患者，随机分为两组，甲组患者采用序贯疗法，乙组患者采用传统的三联疗法，对比分析两种治疗方法的治疗效果。结果甲组患者的幽门螺杆菌（Hp）根除率为92.7%、不良反应发生率为7.3%，与乙组 Hp 根除率80.5%、不良反应发生率26.8%相比差异有统计学意义（P ＜0.05）。结论给予幽门螺杆菌性消化性溃疡患者采用10d 序贯疗法，安全有效，可显著提高患者依从性，应在临床治疗中广泛推广。

Comparative analysis of the efficacy of sequential therapy and triple therapy for Helicobacter pylori peptic ulcer

Objective To analytical investigate the therapeutic effects of sequential therapy and triple therapy on Helicobacter pylori peptic ulcer. Methods 82 patients with H pylori peptic ulcer were selected since the last year in our hospital, and divided into two groups, group A were treated with sequential therapy, and group B were treated with traditional triple therapy. Comparative analysis their curative effects of two treatments methods. Results H pylori eradication rate of group A patients was 92.7%, whose incidence of adverse reactions was 7.3%, and eradication rate of group B was 80.5%, and incidence of adverse reactions was 26.8%,it had significant differences, with statistical significance（P 〈 0.05）. Conclusion Helicobacter pylori peptic ulcer sequential therapy with 10 days is safe and effective, it can significantly improve patients’compliance, should be widely promoted in the clinical treatment.