早期运动干预对新生儿缺氧缺血性脑病神经运动功能恢复的影响

目的探讨改善和促进新生儿缺氧缺血性脑病神经运动功能恢复的辅助疗法。方法将85例新生儿缺氧缺血性脑病患儿随机分为两组：观察组（45例）和对照组（40例），观察组在常规综合药物治疗的基础上加用早期运动干预，对照组单纯常规综合药物治疗。比较两组新生儿行为神经评分（NBNA）、智力发育指数（MDI）和精神运动发育指数（PDI）。结果出生后7d两组患儿NBNA比较差异无统计学意义，14d观察组（38．84±1．56）分]较对照组（36．12±2．23）分]明显增高，两组比较差异有统计学意义。6个月两组MDI比较，差异无统计学意义，而PDI比较差异有统计学意义（90．11±9．97）分和（86．35±11．26）分]；12个月观察组MDI、PDI均较对照组明显增高，差异有统计学意义。结论早期运动干预可促进新生儿缺氧缺血性脑病患儿神经运动功能的恢复，预防和减轻脑损害后遗症，提高生存质量。

The effects of early exercises intervention for nervous movement functional recovery on neonate hypoxic ischemic encephalopathy

Objective To investigate the assistant method for improving and promoting nervous movement functional recovery on neonate hypoxic iscbemic encephalopathy. Methods Eighty-five patients with neonate hypoxic ischemic encephalopathy were divided into two groups： observed group （45 cases） and control group（40 eases）. Observed group added early exercises intervention on basis of routine synthetic drug treatment, compared to control group which just purely synthetic drug treatment with neonatal behavior neurological assessment （NBNA）, mental development index （MDI） and psychomotor development index （PDI）. Results NBNA at 14 days （38.84 ± 1.56）scores] in observed group was significantly higher than that in control group （36.12 ± 2.23）scores]. PDI at 6, 12 months and MDI at 12 months in observed group were significantly higher than those in control group. Conclusion Early exercises intervention can promote nervous movement functional recovery on neonate hypoxic iscbemic encephalopathy, prevent or lessen brain injury sequels, elevate life quality for patients with neonate hypoxic iscbemic encephalopathy.