| 还原型谷胱甘肽对氧化应激所致肝损伤的作用机制 |
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| 引用本文： | 张立婷,何瑜,熊亚墨,唐宽平.还原型谷胱甘肽对氧化应激所致肝损伤的作用机制[J].湖南中医药大学学报,2009,29(8):15-17. |
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| 作者姓名： | 张立婷 何瑜 熊亚墨 唐宽平 |
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| 作者单位： | 张立婷,熊亚星(兰州大学第一医院,甘肃,兰州,730000);何瑜(金川集团有限公司职工医院,甘肃,金昌,737100);唐宽平(号楼门诊部,北京,100034) |
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| 摘 要： | 从氧化应激损伤肝细胞的机制、还原型谷胱甘肽（Glutathione，GSh0的作用机制、GSH在肝脏疾病中的应用三方面描述了氧化应激在肝细胞损伤中的作用，并着重讨论了还原型谷胱甘肽的本质及其作用机制；在临床应用方面，举例说明还原型谷胱甘肽在各种肝病中发挥积极的作用。结果表明GSH作为抗氧化剂和细胞代谢剂，成为临床中重要的治疗和辅助治疗药物。
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| 关 键 词： | 氧应激 还原型谷胱甘肽 肝损伤 |
Mechanisms of Reducibility Glutathlone on Liver Damage Caused by Oxidative Stress |
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| Institution: | ZHANG Li-Ting, HE Yu, XIONG Ya-Xing, TANG Kuan-Ping (First hospital of Lan Zhou University, Gan su, Lan zhou, 730000, China) |
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| Abstract: | The mechanism of the oxidative stress damage liver cells, the mechanism of reduced glutathione （GSH） and applications of GSH in the liver diseases are described in three areas of oxidative stress in liver cell damage and focused on the nature of reduced glutathione and its mechanism; in clinical applications, examples of reduced glutathione in a variety of liver disease playing an active role. The resulfs show that GSH as the antioxidant and the cell metabolism agent, has become an important part of the clinical treatment and the adjuvant therapy drug. |
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| Keywords: | Oxidative Stress Reducibility Glutathlone Liver Damage |
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