| 福氏完全佐剂包裹白细胞介素2和肿瘤坏死因子对小鼠S180肿瘤的抑制作用 |
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| 引用本文： | 黄晋生,范佩芳.福氏完全佐剂包裹白细胞介素2和肿瘤坏死因子对小鼠S180肿瘤的抑制作用[J].肿瘤,1994,14(1):5-8. |
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| 作者姓名： | 黄晋生 范佩芳 |
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| 作者单位： | 第三军医大学西南医院消化实验室，上海生物化学研究所，北京市海军总医院肿瘤临床实验室 |
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| 摘 要： | 本文报道一种新的免疫治疗方法。用福氏完全佐剂（Ｆｒｅｕｎｄ＇ｓ ｃｏｍｐｌｅｔｅ ａｄｊｕｖｅｎｔ，ＦＣＡ）包裹白细胞介素２（ｌｎｔｅｒｌｅｕｋｉｎ ２，ＩＬ－２）及／或肿瘤坏死因子（Ｔｕｍｏｒ Ｎｅｃｒｏｓｉｓ Ｆａｃｔｏｒ，ＴＮＦ）作了抗Ｓ１８Ｏ肉瘤的体内抗瘤实验。结果表明：ＩＬ－２及／或ＴＮＦ经佐剂包裹后，可明显减轻其毒副作用，并显著提高ＩＬ－２及／或ＴＮＦ的抗瘤作用。
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| 关 键 词： | 福氏完全佐剂 IL－2 TNF S18O肉瘤 |
Antitumor Effect of IL-2 and/or TNF Entrapped by FCA on S18O Sarcoma Bearing Mice |
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| Huang Jin-sheng,Wei-wen,Liu Xin-yuan et al..Antitumor Effect of IL-2 and/or TNF Entrapped by FCA on S18O Sarcoma Bearing Mice[J].Tumor,1994,14(1):5-8. |
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| Authors: | Huang Jin-sheng Wei-wen Liu Xin-yuan |
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| Abstract: | This paper reported a method of immunotherapy for treating tumors in vivo.Interleukin 2 (IL-2) and/or tumor necrosis factor(TNF) entrapped by Freund's complete adjuvant(FCA) was administered to S180 sarcoma bearing mice. The result showed that this method. improved the antitumor capacity and lowered significantly the adverse effects. |
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| Keywords: | Immunotherapy Interleukin 2 Tumor necrosis factor Freund's complete adjuvant Murine S180 sarcoma |
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