中国内地首例甲型H1N1流感患者115例密切接触者医学观察分析

目的：通过对首例甲型H1N1流感密切接触者临床医学观察发现二代患者,为大规模临床医学观察积累经验和参考。方法：对首例甲型H1N1流感患者密切接触者115例的临床医学观察资料进行回顾性分析。结果：115例密切接触者中,有6人出现不同程度咽充血、咽部疼痛症状,其中1例为糖尿病患者、2例为高血压患者;1例左前臂疱疹,1例口腔溃疡,4例结膜充血;观察第3天1例出现精神抑郁,1例出现情绪激动;观察第4天2例多次要求提前解除隔离,多例关心何时解除隔离。七日医学观察期间115例密切接触者均无咽痛、咳嗽、鼻塞等症状,体温均正常,情绪稳定,未发现二代患者。结论：对甲型H1N1流感患者的密切接触者进行临床医学观察是必要的,有助于发现二代患者,疾控中心（CDC）采样与临床医学观察和心理干预的有效结合,给传染病医学观察提供宝贵的经验和有效的工作模式。

Analysis of Clinical Medicine Observation of the First Imported Case of Mainland China Influenza A/H1N1 Influenza 115 Close Contacts

Objective： To discover two generation of patients through clinical medicine observation to the first example A/H1N1 influenza close contacts,for large-scale clinical medicine observation accumulation experience and reference.Methods：To retrospectively analyze the clinical medicine observation data of the first example A/H1N1 influenza patient 115 close contacts.Results：In 115 close contacts,6 cases appeared the varying degree to swallow hyperemia and swallow ache,of them 1 case had diabetes,2 cases had elevated blood pressure.1 case left forearm blister measles,1 case had oral cavity ulcer,4 cases had hyperemic conjunctiva.On the 3rd day 1 case appeared the spirit to be despondent and another had the mood to be excited.On the 4th day 2 cases requested to relieve the isolation ahead of time many times,the multiples cared about when relieve the isolation.115 close contacts did not have symptoms such as swallow ache,cough,stuffy nose.their body temperature is normal,their mood is stable.No two generation of patients was discovered.Conclusions：The clinical medicine observation to the A/H1N1 influenza patient＇s close contact is necessary.It is helpful to discover two generation of patients.The effective union between sample collection by CDC and the clinical medicine observation and the psychological intervention,provides the precious experience and the effective working pattern to the infectious disease medical observation.