深部痛点阻滞在顽固性癌痛中的临床研究

目的：探讨深部痛点阻滞在治疗顽固性癌痛患者中的作用。方法：将156例顽固性癌痛患者,随机分为深部痛点阻滞组及对照组,每组78例。深部痛点阻滞组根据疼痛部位,应用软组织外科学理论找出相应压痛点,给予痛点深部阻滞治疗;对照组找出压痛点但仅按三阶梯用药原则给予口服药物治疗。结果：深部痛点阻滞组及对照组两组患者经治疗后疼痛控制均较理想（深部痛点阻滞组VAS1.3,对照组VAS1.7）,但是深部痛点阻滞组吗啡用量明显少于对照组（吗啡日平用量深部痛点阻滞组为33.5mg,对照组为152.87mg）。便秘的发生率深部痛点阻滞组为53.84%,对照组为76.92%。结论：深部痛点阻滞能较好的控制顽固性癌痛,同时可明显减少吗啡的用量,副作用相对发生要少。

The Clinical Investigation of the Deep-Pressed Pain Points Injection on the Refractory Cancer Pain

Objective：To investigate the effect of the deep-pressed pain points injection on the refractory cancer pain and provide reference for relieving the cancer pain.Methods：One hundred and fifty-six patients with refractory cancer pain were diagnosed by the soft tissue surgery,finding the pain point by pressing deeply,the patients with deep-pressed pain points were divided into deep-pressed pain points injection group and control group randomly,The patients in deep-pressed pain points injection group were treated with deep-pressed pain points injection;the patients in control group were treated with drugs according with the WHO analgesic ladder.Results：The patients in deep-pressed pain points injection group got the same pain relief as those in control group （VAS 1.3 in deep-pressed pain points injection group,1.7 in control group ）,but the daily dose of morphine in deep-pressed pain points injection group was less than that incontrol group （morphine 33.5mg/day in deep-pressed pain points injection group,152.87mg/day in control group ） significantly.There was 53.84% patients with constipation in deep-pressed pain points injection group,76.92% in control group.Conclusion：The refractory cancer pain can be controlled effectively by the deep-pressed pain point injection and the daily dose of morphine to control the cancer pain is decreased significantly.The side effect in deep-pressed pain points injection group was less than that in control group.