芬太尼和咪唑安定分别与异丙酚联合用药与胃镜检查

目的：讨论胃镜检查中更加舒适的一种镇静镇痛方法。方法：芬太尼-异丙酚为Ⅰ组，咪唑安定一异丙酚组为Ⅱ组。观察记录各组术中的反应、胃镜操作时间、麻醉药物起效时间、苏醒时间和清醒时间，检查前中后BP、HR和SpO2的变化，及术后问卷调查。结果：Ⅰ组药物的起效快，受检者苏醒及清醒时间短，术中不适反应少，与Ⅱ组比较有统计学意义（P〈0．01）。结论：镇静无痛苦胃镜检查中芬太尼一异丙酚联合用药更舒适。

Associated Medication of FentanyI-Propofol and Midazolam-Propofol and Gastroscopy

Objective： To search for a sedative and analgesic method that is more comfortable for gastroscopy. Methods： Patients were randomly divided into fentanyl-propofol（Group Ⅰ ） and midazolam-propofol（Group Ⅱ ）. The reaction of patients, the effect of sedation, the variation of Bp, SaO2 and HR were observed. Questionnaires were proceeded after gastroscopy. Results： The time of patients coming into unconsciousness in group Ⅰ was much shorter than groupⅡ （P〈0.01）. The time of patients regaining consciousness in group Ⅰ was much shorter than group Ⅲ （P〈0.01）. The probability of discomfort in group Ⅰ was lower than group Ⅱ （P〈0.01）. Conclusion： Associated of fentanyl and propofol is more comfortable for painless gastroscopy.