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血管紧张素Ⅱ受体拮抗剂对阵发性房颤患者P波离散度的影响
引用本文:赵国忠,陈晨,冯小兰,林蔚,瞿龙. 血管紧张素Ⅱ受体拮抗剂对阵发性房颤患者P波离散度的影响[J]. 华西医学, 2009, 0(6): 1445-1446
作者姓名:赵国忠  陈晨  冯小兰  林蔚  瞿龙
作者单位:四川省科学城医院心内科,四川绵阳621900
摘    要:目的:探讨血管紧张素Ⅱ受体拮抗剂(ARB)对PAF患者P波离散度的影响。方法:观察48例阵发性AF患者的最宽P波和P波离散度,并与ARB干预治疗3个月后进行对比分析。结果:ARB治疗3个月后最宽P波、P波离散度及P波离散度≥40 ms的例数与治疗前比较差异有统计学意义(P〈0.05或〈0.01)。结论:ARB能减轻PAF患者心房结构重构及电重构,减少AF的发生。

关 键 词:血管紧张素Ⅱ受体拮抗剂  阵发性AF  P波离散度

Effects of Angiotensin Ⅱ Receptor Blocker on P Wave Deviation Degree in Patients with Paroxysmal Atrial Fibrillation
Affiliation:ZHAO Guo-zhong, CHEN Chen, FENG Xiao-lan, et al. (Science City Hospital, Mianyang Sichuan 621900, China)
Abstract:Objective: To investigate the effect of angiotensin Ⅱ receptor blocker on P wave deviation degree in patients with paroxysmal atrial fibrillation.Methods: Forty-eight patients with paroxysmal atrial fibrillation had taken angiotensin Ⅱ receptor blocker for three months.The widest P wave and P wave deviation degree was measured before and after treatment.Results: After treatment the widest P wave,P wave deviation degree and the cases of P wave deviation degree ≥40 ms were significantly reduced compared with those before treatment(P〈 0.05 or P〈 0.01).Conclusion: Angiotensin Ⅱ receptor blocker lessens atrial structure and electric remodeling,and decreases incidence of atrial fibrillation.
Keywords:angiotensin Ⅱ receptor blocker  paroxysmal atrial fibrillation  P wave deviation degree
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