阻塞性睡眠呼吸暂停综合征患者夜间心律失常的研究

目的：了解阻塞性睡眠呼吸暂停综合症（OSAHS）患者夜间心律失常的发生情况、常见类型及相关因素。方法：对67例睡眠打鼾患者同步进行动态心电图及多导睡眠图监测。以呼吸暂停指数及夜间最低氧饱和度将研究对象进行分组,比较分析夜间心律失常发生率及发生类型并进一步分析夜间心律失常的相关因素。结果：OSAS组的夜间心律失常发生率显著高于单纯鼾症患者。随着OSAS加重,呼吸暂停低通气指数逐渐增大,夜间氧饱和度下降越明显,心律失常发生率升高,发生时间延长、恶性程度增加,尤其以缓慢型心律失常的发生率增多。结论：OS-AHS患者夜间心律失常的发生率及严重程度与OSAHS严重程度呈正相关,夜间心律失常的诱发与呼吸暂停低通气指数及低氧血症密切相关。应重视夜间心律失常患者合并存在的OSAHS的诊治。

Nocturnal Arrhythmia in Obstructive Sleep Apnea-Hypopnea Syndrome

Objective：To study the incidence,type and related factors of nocturnal arrhythmia in Obstructive sleep apnea-hypopnea syndrome.Methods：Sixty-seven cases with snoring during sleep were included in the study.Polysomnography and Synchronous Holter monitoring were executed.The incidence,type and related factors of nocturnal arrhythmia in Obstructive sleep apnea-hypopnea syndrome were analyzed in different severity groups according to apnea-hypopnea index and lowest nocturnal oxygen saturation.Results：Groups with OSAHS have higher incidence of nocturnal arrhythmia than simply snoring group. With increasing of OSAHS severity, the incidence, duration, severity of nocturnal arrhythmia increase sharply, too, especially in bradycardia. Conclusion：There was positive relationship between OSAHS severity and the incidence as well as severity of nocturnal arrhythmia. AHI and hypoxia may lead to arrhythmia in sleep. More attention should be paid to the treatment of OSAHS,which apparently nocturnal arrhythmia.