| 车前子对高脂血症大鼠血脂水平及抗氧化作用的影响 |
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| 引用本文： | 张杰,李兴琴,王素敏,朱树森.车前子对高脂血症大鼠血脂水平及抗氧化作用的影响[J].中国新药杂志,2005,14(3):299-301. |
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| 作者姓名： | 张杰 李兴琴 王素敏 朱树森 |
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| 作者单位： | 河北省医学科学院生化研究室,石家庄,050021 |
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| 摘 要： | 目的:研究车前子对高脂血症大鼠血脂水平及抗氧化作用的影响.方法:用高脂饲料喂饲健康成年SD大鼠3个月,诱发高脂血症的同时,分别加入不同剂量的车前子,观察其对血脂及抗氧化作用的影响.结果:车前子可明显降低大鼠血清胆固醇(TC)、三酰甘油(TG)和脂质过氧化物(MDA)含量,提高高密度脂蛋白胆固醇(HDL-C)及HDL-C/TC比值,并且还能提高超氧化物歧化酶(SOD)、过氧化氢酶(CAT)活性及一氧化氮(NO)含量.结论:车前子能有效的降低高脂血症大鼠血脂水平,提高抗氧化能力.
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| 关 键 词： | 车前子 血脂 抗氧化物 |
| 文章编号： | 1003-3734(2005)03-0299-03 |
Effects of Plantago phllium on rat serum lipid metabolism and anti-oxidation |
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| ZHANG Jie,LI Xing-qin,WANG Su-min,ZHU Shu-sen.Effects of Plantago phllium on rat serum lipid metabolism and anti-oxidation[J].Chinese Journal of New Drugs,2005,14(3):299-301. |
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| Authors: | ZHANG Jie LI Xing-qin WANG Su-min ZHU Shu-sen |
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| Abstract: | Objective: To study effects of Plantago phllium on serum lipid metabolism and antioxidation. Methods: A hyperlipidaemia model was established by feeding SD adult rats with high lipid diets for 3 months. The Plantago phllium was simultaneously supplemented to rats to evaluate the effects on the reduction of lipid level and anti-oxidation. Results:The rat serum total cholesterol (TC), triglyceride and MDA were reduced and the HDL level and HDL/TC ratio were increased. The activities of superoxide dismutase,catalase and nitric oxide were enhanced. Conclusion: Plantago phllium may contribute to the reduction of hyperlipidaemia and the inhibition of oxidative modification. |
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| Keywords: | Planlago phllium blood lipid antioxidation |
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